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A Textbook of Pharmaceutical Organic Chemistry – II


  • ISBN: 9789395596060
  • Published : August 2022
  • Book Language : English
  • Edition : First
  • Format : Paperback
  • Pages : 190
  • Category:
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A Textbook of Pharmaceutical Organic Chemistry – II

Significant efforts have spent into the book to make it valuable tool in simplified manner for the students of Second Year B. Pharmacy for the subject of Pharmaceutical Organic Chemistry-II. This book really helpful for understanding the all the concepts of Organic Chemistry as per syllabus of Second Year B. Pharmacy laid down by Pharmacy Council of India, New Delhi.
Every chapter includes review questions from previous University exams question papers to help the students for their preparation. Solved questions will be useful to the students; they will be inspired definitely for writing in- semester as well as University Examinations.

1. Benzene and its Derivatives 
a. Analytical, synthetic and other evidences in the derivation of structure of benzene, Orbital picture, resonance in benzene, aromatic characters, Huckel‘s rule.
b. Reactions of benzene – nitration, sulphonation, halogenations reactivity, Friedel crafts alkylation- reactivity, limitations, Friedel crafts acylation.
c. Substituents, effect of substituents on reactivity and orientation of mono substituted benzene compounds towards electrophilic substitution reaction.
d. Structure and uses of DDT, Saccharin, BHC and Chloramine.

2. Phenols, Aromatoc Amines, and Aromatic Acids 
Phenols :
1. Acidity of phenols
2. Effects of substituents on acidity
3. Qualitative tests
4. Structure and uses of Phenol, Cresols, Resorcinol, Naphthols
Aromatic amines :
1. Basicity of amines
2. Effects of substituents on basicity
3. Synthetic uses of aryl diazonium salts
Aromatic Acids :
1. Acidity
2. Effects of substituents on acidity
3. Important reactions of Benzoic acids

3. Stereo Isomerism 
Optical isomerism :
• Elements of symmetry, chiral and achiral molecules
• Optical activity, enantiomerism, diastereoisomerism, meso compounds
• D & L system of nomenclature of optical isomers, sequence rules,
• R & S system of nomenclature of optical isomers
Geometrical isomerism :
• Nomenclature of geometrical isomers (Cis & Trans, E & Z, Syn & Anti systems) Methods of determination of configuration of geometrical isomers.

4. Polynuclear Hydrocarbons 
Synthesis, Reactions, Structures and Medicinal uses of :
• Naphthalene
• Phenanthrene
• Anthracene
• Diphenylmethane
• Triphenylmethane

5. Cycloalkanes Stabilities 
Baeyer‘s strain theory, limitation of Baeyer‘s strain theory, Coulson and Moffitt‘s modification, Sachse Mohr‘s theory (Theory of strainless rings), reactions of cyclopropane and cyclobutane only.

6. Fats and Oils 
• Fatty acids, fats and oils
• Reactions-Salt formation, halide formation, Hydrolysis, Hydrogenation, Saponification
• Rancidity of oils and Drying oils
• Analytical constants- Acid value, Saponification value, Ester value, Iodine value, Acetyl value, Reichert Meissl value


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