1. Recapitulation of Mendelian Genetics.......................7
1.1 Mendel’s work: Selection of Experimental plant.
1.2 Mendelian inheritance: Laws of heredity and their practical applications (Monohybrid cross and Dihybrid cross).
1.3 Test cross and back cross.
2. Non-Mendelian Genetics......................................30
2.1 Concept of gene Interaction: Intra-allelic interactions and Interallelic interactions.
2.2 Dominance and Co-dominance.
2.3 Inter-allelic interactions: Co-dominance and incomplete dominance (concept of epistasis, complimentary factors (9 : 7), supplementary factors (9 : 3 : 4), inhibitory factors (13 : 3), duplicate dominant genes (factors) (15 : 1).
2.4 Lethal genes in Mus musculus.
3. Multiple Allel..................................................50
3.1 Concept and characteristics.
3.2 ABO blood group system, Inheritance of Rh antigen, Erythroblastosis foetalis and their medicolegal importance of these systems.
4. Chromosomes..................................................................62
4.1 Introduction: Morphology and types of chromosomes (based on the position of centromere and involvement in sex determination).
4.2 Chromatin, its structure and its types (Euchromatin and Heterochromatin).
4.3 Giant chromosomes (Polytene chromosome and Lamp brush chromosomes).
4.4 Chromosomal aberrations: Structural (Deletion, duplication, inversion and translocation) and Numerical (Euploidy, monoploidy, polyploidy- autopolyploidy & allopolyploidy and aneuploidymonosomy, nullisomy, trisomy).
5. Sex Determination.........................................87
5.1 Genetically Controlled Sex Determination
5.2 Parthenogenesis & Gynandromorphism
5.2.1 Parthenogenesis
5.2.2 Gynandromorphs
6. Sex Linked Inheritance.........................................................................100
6.1 Sex-linked inheritance
6.2 Examples of Sex-linked inheritance.
7. Introduction to Medical Zoology.........................110
7.1 Definitions
7.2 Branches of Medical Zoology:
7.2.1. Medical Protozoology,
7.2.2. Medical Helminthology,
7.2.3. Medical Entomology.
8. Epidemic Diseases in Human.........................124
8.1 Typhoid.
8.2 Cholera.
8.3 Small pox
9. Vector Borne Diseases in Human..............................143
9.1 Dengue.
9.2 Chicken Guinea.
9.3 Viral Influenza.
9.4 Scabies
10. Microbial Diseases in Human......................166
10.1 Causative organism and clinical features of the Tuberculosis
10.2 Causative organism and clinical features of the Hepatitis
10.3 Causative organism and clinical features of the AIDS.
11. Investigations and Treatments of Human Physiological Disorders....180
11.1 Angiography.
11.2 Angioplasty.
11.3 Dialysis
Annexure……………...........190
Question paper pattern
Glossary- Genetics Terminology
Questions and Problems with solutions in genetics
Multiple Choice Questions
